Product Overview

Sodium Hyaluronate Low Molecular Weight (400-1,000 K Da) is the go-to ingredient for anti-aging and deep hydration skincare formulations. Its shortened polymer chains allow penetration beyond the skin surface into the deeper epidermal layers, delivering moisture where fine lines form. This grades provides sustained, long-lasting hydration rather than surface-only effects, making it essential for serums targeting wrinkle reduction and skin elasticity improvement.

Low MW HA combines well with high and medium MW HA in multi-weight formulations for comprehensive, multi-layer hydration. In food applications, it supports joint health with improved bioavailability. UPOR Biotech provides complete regulatory documentation (COA, MSDS, stability data) with every shipment.

Technical Specifications

PropertySpecification
Product NameSodium Hyaluronate Powder (Low Molecular Weight)
CAS Number9067-32-7
Molecular Weight400 – 1,000 K Da
AppearanceWhite to off-white powder
Purity (HPLC)≥99.0%
pH (0.1% solution)6.0 – 7.5
Loss on Drying≤10.0%
Protein Content≤0.1%
Heavy Metals≤10 ppm
GradeCosmetic Grade & Food Grade
CertificationsISO 9001, c-GMP, FDA, HALAL, KOSHER, COSMOS
StandardsUSP, EP compliant
Packaging1 kg/bag, 5 kg/bag, 25 kg/drum

Key Benefits

Deep Epidermal Penetration

Penetrates into the epidermis delivering moisture below the surface — reduces fine lines and wrinkles from within. Clinical studies show significant improvements in skin elasticity after 4-8 weeks.

Anti-Wrinkle

Sustained Deep Hydration

Provides long-lasting moisture in the lower epidermis, unlike surface-only high MW HA. Maintains skin hydration levels for 24+ hours after application.

24hr Hydration

Easy to Formulate

Low viscosity allows easy dispersion and rapid hydration. Excellent compatibility with other active ingredients — peptides, vitamins, niacinamide, and botanical extracts.

Formulator-Friendly

Clinically Validated

Supported by published clinical studies demonstrating wrinkle depth reduction, improved skin firmness, and increased skin elasticity at 0.1-0.5% usage rates.

Clinical Data

Applications

💧

Anti-Aging Serums

Core active in wrinkle-reduction serums. Penetrates deeply for sustained anti-aging hydration.

👀

Eye Creams & Treatments

Targets fine lines in the delicate periorbital area. Low MW penetrates thin eyelid skin effectively.

💄

Sheet Mask Essences

Delivers deep hydration during extended mask wear time. Penetrates while the mask prevents evaporation.

🧴

Anti-Aging Creams

Combined with high MW HA for surface film + deep penetration — complete anti-aging moisturization.

💊

Beauty Supplements

Oral hyaluronic acid with good bioavailability. Supports skin hydration from within.

🔬

Professional Treatments

Used in mesotherapy and professional-grade serums for cosmetic clinics and aestheticians.

FAQ

Low MW HA (400-1,000 K Da) is the premier anti-aging grade — designed for deep epidermal penetration, sustained hydration, and clinically validated wrinkle reduction. It is the core active ingredient in premium anti-aging serums and eye treatments.

Yes. Unlike high MW HA which stays on the surface, low MW HA penetrates into the epidermis to hydrate from within. Published clinical studies confirm significant improvements in wrinkle depth, skin firmness, and elasticity after 4-8 weeks of consistent use at 0.1-0.5%.

Yes — this is a best practice. Many premium serums combine high MW HA (surface film + instant plumping) with low MW HA (deep penetration + sustained anti-aging). This delivers both immediate and long-term benefits in a single product.

ISO 9001:2015, c-GMP, FDA-registered, HALAL, KOSHER, COSMOS certified. USP and EP compliant with full COA, MSDS, and lot traceability provided with every order.

Request a Quote